Study: The Association between Vitamin D Status and Autism Spectrum Disorder (ASD)

The association between vitamin D status and autism spectrum disorder (ASD) is well-investigated but remains to be elucidated. We quantitatively combined relevant studies to estimate whether vitamin D status was related to ASD in this work. PubMed, EMBASE, Web of Science, and the Cochrane Library were searched to include eligible studies. A random-effects model was applied to pool overall estimates of vitamin D concentration or odds ratio (OR) for ASD. In total, 34 publications involving 20,580 participants were identified in this present study. Meta-analysis of 24 case-control studies demonstrated that children and adolescents with ASD had significantly lower vitamin D concentration than that of the control group (mean difference (MD): -7.46 ng/mL, 95% confidence interval (CI): -10.26; -4.66 ng/mL, p < 0.0001, I² = 98%). Quantitative integration of 10 case-control studies reporting OR revealed that lower vitamin D was associated with higher risk of ASD (OR: 5.23, 95% CI: 3.13; 8.73, p < 0.0001, I² = 78.2%). Analysis of 15 case-control studies barring data from previous meta-analysis reached a similar result with that of the meta-analysis of 24 case-control studies (MD: -6.2, 95% CI: -9.62; -2.78, p = 0.0004, I² = 96.8%), which confirmed the association. Furthermore, meta-analysis of maternal and neonatal vitamin D showed a trend of decreased early-life vitamin D concentration in the ASD group (MD: -3.15, 95% CI: -6.57; 0.26, p = 0.07, I² = 99%). Meta-analysis of prospective studies suggested that children with reduced maternal or neonatal vitamin D had 54% higher likelihood of developing ASD (OR: 1.54, 95% CI: 1.12; 2.10, p = 0.0071, I² = 81.2%). These analyses indicated that vitamin D status was related to the risk of ASD. The detection and appropriate intervention of vitamin D deficiency in ASD patients and pregnant and lactating women have clinical and public significance.

Source: https://pubmed.ncbi.nlm.nih.gov/33383952/

On This Day in History…

Italy to Ration Use of Air Conditioning, Heat, to Wean Country Off Russian Power

2 years ago

Two weeks after Italians were told they’d have a choice between “air conditioning or peace”, the government appears to have made the choice for them, introducing rationing of AC and heat in a bid to reduce the nation’s dependence on imported Russian energy. From May 21st, public buildings such as government offices and schools in Italy will be limited on the degree to which they can use heating and cooling to regulate the temperature in a bid to reduce energy use. In the summer, air conditioning units will … Read More

Study: Soft Bedding a Grave Danger to Sleeping Babies

5 years ago

Almost 70% of babies who died from sleep-related suffocation between 2011 and 2014 did so because of soft bedding, a new study reveals. The finding underscores physicians’ urgent message to new parents that babies should sleep only in cribs or bassinets free of blankets, toys and other potential hazards. Unintentional suffocation is the No. 1 cause of injury death in babies less than a year old in the United States, with more than 80% of cases occurring in bed. The new study, from a University of Virginia Health … Read More

Ronald Bernard, a Former Elite Dutch Banker who Facilitated Money Laundering & Tax Avoidance for Elites, Secret Service, Governments, & Terr…

7 years ago

The Alternative Media have long asserted that an international cabal of satanists controls our world. Now, a credible whistleblower has come forth, testifying to the cabal’s existence. He is a former elite Dutch banker named Ronald Bernard. Below is an interview of Bernard in Dutch, with English subtitles, followed by a transcript. The interview was conducted in cooperation with De Vrije Media by Irma Schiffers, a former radio host, author, and columnist from The Netherlands. In the interview, Bernard said that he came from a family with an … Read More

Pat Tillman, Propagandized as NFL American War Hero to Manufacture War Support, is Murdered Before Going Public in Opposition to the Afghan War

20 years ago

Death of Pat Tillman, a complete fairytale that was carefully packaged by the mass media so as to elicit a resurgence of support for the wars in Iraq and Afghanistan at a time when public sentiment had begun to turn against the occupations. During Tillman’s second deployment to Afghanistan he was killed by what the U.S. military initially claimed was a Taliban ambush, but later emerged that the ambush story had been concocted by the Pentagon in an attempt to exploit Tillman’s death for pro-war propaganda. Subsequent investigations … Read More

Army Hearings Begin as Joe McCarthy Investigates the Army’s ‘Softness’ on Communism and Communist Infiltration. A Smear Campaign Ens…

70 years ago

Senator Joseph McCarthy begins hearings investigating the United States Army, which he charges with being “soft” on communism. In the same month and year that the damaging Reece Committee report (April 30, 1954) was released, the same globalist and communist forces combined in identical manner to destroy Senator Joseph McCarthy (R-Wis.). Anthony Lukas, writing for the New York Times, a CFR stronghold and one of McCarthy’s harshest critics, noted that “as McCarthy bulled ahead it became clear that his real target was the Eastern Establishment, which had run … Read More

The Oklahoma Land Rush of 1889: Boomers and Sooners Rush to Claim Former Native American Land

135 years ago

In 1889, as many as 50 thousand settlers poured into Oklahoma hoping to stake claim to a portion of nearly two million acres opened for settlement by the U.S. Government. Many had campaigned the federal government to open the land for settlement and were known as Boomers. The land, formerly occupied by Native Americans, was considered Unassigned Lands after the federal government forcibly relocated many Native American tribes. On April 22, 1889, at noon sharp, a bugle sounded, and hopeful settlers surged across the territory line. The number of … Read More

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